Stem Cell Therapy for Back Pain

Non-Invasive Therapy for Spinal Pain and Injuries

Stem Cell Therapy for Back Pain Overview

Among our entire musculoskeletal system, our spine is probably the most complicated and most often damaged. For years doctors have performed treatments, therapies and surgical procedures in an attempt to repair damage to the spine. but all too often, their attempts produce less than acceptable results. And recovering from spinal surgery can require up to a year. In recent years however, a new therapy for spinal pain is showing promising results. In some cases, spinal conditions can be improved with stem cell therapy for back pain. An approach that makes use of the body’s own healing power.

Mesenchymal Stem Cells are the specific type of stem cells within our body that replicate and differentiate into the bone, cartilage, connective tissues and muscles cells that are all key components of the spine. The orthopedic stem cell therapy that we provide at Pangenics Regenerative Center is a safe, minimally-invasive procedure where we harvest millions of mesenchymal stem cells from a small amount your body’s adipose tissue, (body fat), then inject them directly into damaged or injured areas of the spine and via IV so they can work to repair the damaged bone, cartilage, connective tissues and muscles cells that make up the spine. The following is a more detailed explanation of the stem cell therapy for back pain available at Pangenics Regenerative Center.

How Mesenchymal Stem Cell Therapy for Back Pain Works

Mesenchymal stem cell therapy for the spine is based on the same knowledge and understanding that mesenchymal stem cell therapy for joints is based on. We know that when bone cells, cartilage cells, and connective tissue cells such as cartilage cells and tendon cells are damaged or begin to die, they call for help using paracrine signaling. We also know that mesenchymal stem cells respond to these signals from cells of the mesenchyme, hence their name. However, age and other conditions within our bodies can slow and interfere with this response.

Stem cell therapy is like any other therapy. It is assisting the body’s natural healing process. Stem cell therapy is a process by which millions of mesenchymal stem cells are gathered from one area of a patient’s own body and placed directly into the areas where they are needed. In the case of the spine, to help them quickly respond in mass to the signaling from damaged bone cells, cartilage cells and connective tissue cells. The following is a more detailed explanation of the stem cell therapy for back pain that is available at Pangenics Regenerative Center.

Learn more about Mesenchymal Stem Cells.

How Mesenchymal Stem Cell Therapy for Back Pain Works

Mesenchymal stem cell therapy for the spine is based on the same knowledge and understanding that mesenchymal stem cell therapy for joints is based on. We know that when bone cells, cartilage cells, and connective tissue cells such as cartilage cells and tendon cells are damaged or begin to die, they call for help using paracrine signaling. We also know that mesenchymal stem cells respond to these signals from cells of the mesenchyme, hence their name. However, age and other conditions within our bodies can slow and interfere with this response.

Stem cell therapy is like any other therapy. It is assisting the body’s natural healing process. Stem cell therapy is a process by which millions of mesenchymal stem cells are gathered from one area of a patient’s own body and placed directly into the areas where they are needed. In the case of the spine, to help them quickly respond in mass to the signaling from damaged bone cells, cartilage cells and connective tissue cells. The following is a more detailed explanation of the stem cell therapy for back pain that is available at Pangenics Regenerative Center.

Learn more about Mesenchymal Stem Cells.

How We Harvest Millions
of Your Live Mesenchymal Stem Cells

Now that we understand how our body uses mesenchymal stem cells to repair and replace bone, cartilage, connective tissue and muscle cells, the next question is how do we help them get to the areas where they are needed? Simply put, we physically move as many of them to the treatment area as possible. And there are a few different ways to do this. Some more effective than others.

The first step in stem cell therapy for back pain at Pangenics Regenerative Center is much different than most other stem cell therapy centers. While most centers today opt for either harvesting mesenchymal stem cells from bone marrow, which yields less than 10,000 viable cells per 2 ounces of bone marrow, or purchasing frozen umbilical cord cells that can lead to possible genetic and epigenetic changes, and low cell survival rates. Pangenics stem cell physicians harvest millions of live viable mesenchymal stem cells from adipose tissue, (body fat).

Our extensive research and the hundreds of physicians that participate with us in national IRBs, (Institutional Review Boards) have repeatedly verified that harvesting mesenchymal stem cells from the patient’s own adipose tissue, (body fat) allows for the collection of 10s of millions of live viable mesenchymal stem cells.

Our particular process is a 38 step process that allows us to harvest up to 50 million live, viable mesenchymal stem cells. Millions more than can be harvested from bone marrow, and that have a much higher survival rate because they are transferred from one area of the body to the area of therapy in the same procedure and not frozen and thawed.

We begin by collecting a small amount of body fat using a closed sterile, FDA approved fat collection system called Adivive®. This allows us to harvest what we refer to as SVF or Stromal Vascular Fraction.

Stromal Vascular Fraction, SVF Explained

Stromal: Best explained as a pinch of fat. The first layer of fat directly beneath the skin.

Vascular: Within the Stromal fat, there are tiny blood vessels where mesenchymal stem cells are found in abundance.

Fraction: The heterogeneous group of cells derived from the fat that contains mesenchymal progenitor/stem cells, preadipocytes, endothelial cells, pericytes, T cells, and M2 macrophages.

The SVF then goes through all the remaining steps that purify and isolate the mesenchymal stem cells. Once the mesenchymal stem cells are completely separated from the stromal vascular fraction, a NucleoCounter® Cell Counter is used to count the viable, live mesenchymal stem cells to assure needed quantities are present. The Magellan® Autologous Platelet Separator is then used to filter platelets and seven different growth factors from a small amount of the patient’s blood. This produces Platelet Rich Plasma, (PRP). The Patient’s PRP and mesenchymal stem cells are combined. PRP is added to the stem cells to help them survive the transfer and maximize the effects of the therapy.

Magellen Platelet Separator

Magellen Platelet Separator

The Magellan Platelet Separator is used to produce platelet rich plasma, (PRP) from a small amount of the patient’s blood. The Magellan Platelet separator filters the blood to collect platelets and seven different growth factors from the patient’s blood which is them mixed with the patient’s mesenchymal stem cells. This step helps the mesenchymal stem cells survive, multiply and become replacement cells.

NucleoCounter NC-200 Cell Counter

NucleoCounter NC-200 Stem Cell Counter

The NucleoCounter Stem Cell Counter is used to identify the total number of live, viable mesenchymal stem cells before they are used in therapy. The exact number of live, viable stem cells harvested from each patient and used for their stem cell therapy is very important and is documented in the IRBs we are participating in.

Millions of Live, Viable Mesenchymal Stem Cells Verified

The mesenchymal stem cell count below is from a patient’s records. During this patient’s therapy, we successfully harvested over 17 million live mesenchymal stem cells from only 2 ounces of the patient’s body fat.

Viable Stem Cell Confirmation Counts

Stem Cell Therapy is Performed

The final step of stem cell therapy for back pain can now be performed. Millions of your own live, viable mesenchymal stem cells have been collected and isolated. They have been counted to verify needed quantities, and they have been nourished with platelets and seven different growth factors, (PRP). Millions of your stem cells are now ready to do their job and are injected directly into the joints targeted for therapy and also administered intravenously to maximize the therapy. Once the injections and or IV has been administered, the therapy is complete. There are no side effects and patients are able to drive home or back to work shortly after their therapy.

What Our Patients Are Saying

Dr. Lewis J. Obi, Dr. Kenneth Eaddy and the experienced medical staff at Pangenics have been helping patients reduce and eliminate painful joint and back conditions and get back to doing the things they enjoy for over 15 years. And many of their patients share their stories about how the stem cell therapy they received at Pangenics gave them their life back and allowed them to avoid invasive surgery. This is Ann’s story about how stem cell therapy allowed her to avoid a second knee replacement procedure.

More Stem Cell Patient Reviews

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